Non-survivor patients with malignant middle cerebral artery infarction showed persistently high serum malondialdehyde levels
نویسندگان
چکیده
منابع مشابه
Serum Malondialdehyde Levels in Patients with Malignant Middle Cerebral Artery Infarction Are Associated with Mortality
OBJECTIVE Malondialdehyde (MDA) is an end-product formed during lipid peroxidation, due to degradation of cellular membrane phospholipids. MDA is released into extracellular space and finally into the blood; it has been used as an effective biomarker of lipid oxidation. High circulating levels of MDA have been previously described in patients with ischemic stoke than in controls, and an associa...
متن کاملAssociation between Serum Soluble CD154 Levels and Mortality in Patients with Malignant Middle Cerebral Artery Infarction
BACKGROUND CD154 and its soluble counterpart (sCD154) are proteins of the tumor necrosis factor (TNF) family and exhibit proinflamatory and procoagulant properties. Higher circulating sCD154 levels have been found in ischemic stroke patients than in controls. However, the association between circulating sCD154 levels and mortality in ischemic stroke patients has not been reported, and was the f...
متن کاملMalignant middle cerebral artery infarction.
PURPOSE OF REVIEW This review will report on the new aspects of management of 'malignant' middle cerebral artery (MCA) infarctions. RECENT FINDINGS Large MCA infarctions have been associated with high death rates for years. The most reliable predictors of a 'malignant' course are hypodensity in more than 50% of the MCA territory on computed tomography as well as stroke volume greater than 145...
متن کاملSerum tissue inhibitor of matrix metalloproteinase-1 levels are associated with mortality in patients with malignant middle cerebral artery infarction
BACKGROUND In the last years, circulating matrix metalloproteinases (MMP)-9 levels have been associated with functional outcome in ischemic stroke patients. However the prognostic value of circulating levels of tissue inhibitor of matrix metalloproteinases (TIMP)-1 and MMP-10 in functional outcome of ischemic stroke patients has been scarcely studied. In addition, to our knowledge, serum MMP-9,...
متن کاملSerum S100B predicts a malignant course of infarction in patients with acute middle cerebral artery occlusion.
BACKGROUND AND PURPOSE Early predictors of infarct volume may improve therapeutic decisions in patients with acute cerebral ischemia. We investigated whether measurements of serum astroglial protein S100B can predict a malignant course of infarction in acute middle cerebral artery (MCA) occlusion. METHODS We included 51 patients (24 women, mean age 69.1+/-12.4 years) admitted within 6 hours a...
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ژورنال
عنوان ژورنال: BMC Neurology
سال: 2019
ISSN: 1471-2377
DOI: 10.1186/s12883-019-1479-z